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On the other hand, berberine can inhibit ERK phosphorylation (Lu et al., 2010), and induce the phosphorylation of Liver kinase B1 (LKB1) (Ser428), calcium/calmodulin-dependent protein kinase II (CaMKII) (Thr286), and AMPK (Thr172) (Lu et al., 2010)

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